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Sat05192012

Last update06:59:34 PM

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Tysabri (natalizumab) approved for MS

* antibody that makes it difficult for immune system cells to
move into the brain and spinal cord
* for relapsing remitting MS that has not responded
to other treatment
* reduces relapse rate
* IV infusion once every four weeks
* 1/3 of patients improve in disability, suppresses 90% of MRI disease
* increases risk (1:1000) of viral infection of the brain
* infrequent side effects: headache, pain, fatigue, diarrhea, depression
* approved in 2006

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